Effect of periodontal treatment on lipidic profile of obese patients with chronic periodontitis

• Grant number: 10/17784-6
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2011
• End date: June 30, 2012
• Field of knowledge: Health Sciences - Dentistry - Periodontology
• Principal Investigator: Elizangela Partata Zuza
• Grantee: Elizangela Partata Zuza
• Host Institution: Centro Universitário da Fundação Educacional de Barretos (UNIFEB). Fundação Educacional de Barretos (FEBA). Barretos , SP, Brazil
• Associated researchers: Iracilda Zeppone Carlos ; Mariana Fabricio ; Valdir Gouveia Garcia

Abstract

Studies have been showed that the hyperlipidemia is associated to the periodontal disease and that the obesity can affect even more the dislipidemy levels, increasing the total cholesterol, triglycerides and low-density lipoprotein cholesterol. There are evidences that the periodontal treatment may improve metabolic control of hyperlipidemia. The aim of this study will be to evaluate the effect of nonsurgical periodontal treatment on lipid profile in obese patients with chronic periodontitis. Patients will be divided into four groups: group 1 - Obese with chronic periodontitis (n = 25); group 2 - normal weight with chronic periodontitis (n = 25); group 3 - Obese without periodontal disease (n = 25) and group 4 - Normal weight without periodontal disease (n = 25). The following clinical periodontal parameters will be evaluated: plaque index (VPI), bleeding index (GBI), gingival recession (GR), probing depth (PD) and clinical attachment level (CAL). Blood samples will be collected to verify the lipid profile of patients, analyzing the levels of triglycerides, total cholesterol, high-density lipoprotein (HDL) and low-density lipoprotein (LDL). The non-surgical periodontal treatment will be performed in groups 1 and 2, whereas in the groups 3 and 4 it will be perfomed prophylaxis and oral hygiene instructions at regular intervals. The periodontal parameters and lipid levels will be assessed before and 3 months after the completion of periodontal treatment. The statistical analysis will be performed considering the normality of the data, with a significance level of 5%. (AU)