Spatial analysis of the occurrence of primary bloodstream infections caused by multi-resistant bacteria in intensive care units of the State of São Paulo

• Grant number: 11/19128-1
• Support Opportunities: Regular Research Grants
• Start date: March 01, 2012
• End date: May 31, 2014
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Anna Sara Shafferman Levin
• Grantee: Anna Sara Shafferman Levin
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Francisco Chiaravalloti Neto ; Icaro Boszczowski

Abstract

Although it is generally believed that there is an intimate association between the use of antimicrobial drugs and bacterial resistance, this has not been completely established. There are no populational studies designed to evaluate this association. The aim of our study is to describe the profile and tendency of bacterial resistance in bloodstream infections that occurred in intensive care units in all the State of São Paulo from March 2009 through February 2012 and to examine its geographic distribution. We intend to evaluate potential explanations for the distribution: a- consumption of antimicrobial drugs within hospitals and in the community; b- Human development index; c- Maternal and infant mortality; d- Resources of the hospitals; e- Availability of healthcare professionals within the area; f- Regional revenue; g- Per capita income. The sources of data will be: - infection data: State-wide program of notification of nosocomial infections;- consumption of antimicrobial drugs: data obtained by hiring a specialized company;- other data : national census done in 2010.This study is a cooperation between the Medical and the Public Health Schools of the University of São Paulo and its duration is estimated to be 2 years. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ÍCARO BOSZCZOWSKI; FRANCISCO CHIARAVALLOTI NETO; MARTA BLANGIARDO; OSWALDO SANTOS BAQUERO; GERALDINE MADALOSSO; DENISE BRANDÃO DE ASSIS; THAIS OLITTA; ANNA S. LEVIN. Total antibiotic use in a state-wide area and resistance patterns in Brazilian hospitals: an ecologic study. Brazilian Journal of Infectious Diseases, v. 24, n. 6, p. 479-488, 2021-01-15. (11/19128-1)

MOURA, MARIA L.; BOSZCZOWSKI, ICARO; BLAQUE, MANUELA; MUSSARELLI, RAFAEL M.; FOSSALUZA, VICTOR; PIERROTTI, LIGIA C.; CAMPANA, GUSTAVO; BRANDILEONE, MARIA C.; ZANELLA, ROSEMEIRE; ALMEIDA, SAMANTA C. G.; et al. ffect on Antimicrobial Resistance of a Policy Restricting Over-the-Counter Antimicrobial Sales in a Large Metropolitan Area, Sao Paulo, Brazi. Emerging Infectious Diseases, v. 28, n. 1, p. 180-187, JAN 2022. (11/19128-1)

MOURA, MARIA LUISA; BOSZCZOWSKI, ICARO; MORTARI, NAIMA; BARROZO, LIGIA VIZEU; CHIARAVALLOTI NETO, FRANCISCO; LOBO, RENATA DESORDI; PEDROSO DE LIMA, ANTONIO CARLOS; LEVIN, ANNA S.. The Impact of Restricting Over-the-Counter Sales of Antimicrobial Drugs Preliminary Analysis of National Data. MEDICINE, v. 94, n. 38, SEP 2015. (11/19128-1)

KLIEMANN, BRENO S.; LEVIN, ANNA S.; LUISA MOURA, M.; BOSZCZOWSKI, ICARO; LEWIS, JAMES J.. Socioeconomic Determinants of Antibiotic Consumption in the State of Sao Paulo, Brazil: The Effect of Restricting Over-The-Counter Sales. PLoS One, v. 11, n. 12, DEC 12 2016. (11/19128-1)