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Aceptability and continuation rate of use of etonogestrel-releasing contraceptive implant (Implanon) in comparison to the levonorgestrel-releasing intrauterine system (LNG-IUS) and the intrauterine device (IUD) at the Brazilian public service

Grant number: 12/01379-0
Support type:Regular Research Grants
Duration: June 01, 2012 - May 31, 2014
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Luis Guillermo Bahamondes
Grantee:Luis Guillermo Bahamondes
Home Institution: Centro de Atenção Integral à Saúde da Mulher (CAISM). Hospital da Mulher Professor Doutor José Aristodemo Pinotti. Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


The general objective of the study is to compare the aceptability and some clinical events between users of Implanon, TCu380A IUD and the LNG-IUS up to one year of use after insertion. A total of 300 women will participate in the study, being 100 women in each group. The women will be recruited among those who are users of the Family Planning clinic of the CAISM-UNICAMP. All the women will received orientation and information about the changes of menstrual pattern which eventually can occurs during the use of the different contraceptive methods. All the women who chose Implanon, TCu380A IUD and the LNG-IUS will receive instructions to maintain contact with the clinic in case of any complaint related to the insertion of the 3 methods. The follow-up visits will be schedule at 30 ± 7 days afetr insertion to received additional counseling, devoted to the expected bleeding patterns changes with these methods. To avoid eventual distortions, the counseling session will be exactly the same for all the women. The women included in the study will return at the clinic at 6 and 12 months after insertion, for counseling. All the women will kept a mestrual calendar. Reasons for discontinuation will be record from all women who interrupted the study. Comparison between aceptability between the 3 methods will be evaluated by Ç2 test. Aceptability of mesntrual pattern of Implanon and amenorrhea induced by the LNG-IUS will be evaluated by logistic regression. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MODESTO, WALESKA; VALERIA BAHAMONDES, M.; BAHAMONDES, LUIS. A randomized clinical trial of the effect of intensive versus non-intensive counselling on discontinuation rates due to bleeding disturbances of three long-acting reversible contraceptives. Human Reproduction, v. 29, n. 7, p. 1393-1399, JUL 2014. Web of Science Citations: 28.

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