Plasma concentrations of acute phase proteins in Holstein calves with or without clinical signs of enteritis

• Grant number: 12/06053-6
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2012
• End date: June 30, 2013
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Juliana Regina Peiró
• Grantee: Juliana Regina Peiró
• Host Institution: Faculdade de Medicina Veterinária (FMVA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil
• Associated researchers: Luiz Claudio Nogueira Mendes

Abstract

Objectives: to establish reference intervals for these acute-phase proteins in plasma in calves with or without clinical signs of enteritis; and determine whether one or all of these acute-phase proteins could be used as an indicator of prognosis for the development and/or recovery of the disease in calves housed with animals with different age range in the same pasture by means of (SDS-PAGE).Animals: 19 Holstein calves with or without umbilical hernia. Procedures: Plasma samples from calves with (n=7) or without (n=12) clinical signs of enteritis will be evaluated for determination of acute-phase protein concentrations on days 0, 1, 3, 5, and 7 of age. Data from the 2 groups will be compared. Clinical relevance: Values for these acute-phase proteins will be established for each group; and a potential inflammatory biomarker during the disease will be determined in calves with and without clinical signs of enteritis. (AU)