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Cardioinflammatory biomarkers and cardiovascular system: new technologies and epigenetics

Grant number: 12/08622-8
Support Opportunities:Research Grants - Visiting Researcher Grant - International
Start date: August 24, 2012
End date: August 30, 2012
Field of knowledge:Biological Sciences - Physiology - Physiology of Organs and Systems
Principal Investigator:Angelina Zanesco
Grantee:Angelina Zanesco
Visiting researcher: Loren E. Wold
Visiting researcher institution: Ohio State University, Columbus, United States
Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil

Abstract

Despite improvement of new drugs to treat cardiovascular diseases (CVD), the burden of these disease still high in the world population. Therefore, development new technologies and evaluation in the interaction between CVD and cardioinflammatory biomarkers in the ageing process will be a hallmark for better understanding the mechanistic events on the CVD in elderly as well as in old rats. We also aiming to study the influence of epigenetics (lifestyle changing) on the expression of some proteins controlling cardiovascular system, including AKt (PKB) and endothelial nitric oxide enzyme. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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