| Grant number: | 16/25309-2 |
| Support Opportunities: | Regular Research Grants |
| Start date: | May 01, 2017 |
| End date: | April 30, 2018 |
| Field of knowledge: | Health Sciences - Medicine - Surgery |
| Principal Investigator: | Paulo Celso Bosco Massarollo |
| Grantee: | Paulo Celso Bosco Massarollo |
| Host Institution: | Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated researchers: | Alfredo Luiz Jacomo ; Ernesto Sasaki Imakuma ; Fabricio Ferreira Coelho ; George Felipe Bezerra Darce |
Abstract
In piggyback liver transplantation, the anastomosis between the cranial portion of the graft inferior vena cava (IVC) and the common stump of the recipient middle and left hepatic veins (ME) has a higher frequency of hepatic venous outflow obstruction. This incidence decreases when a cavo-caval side-to-side anastomosis or the ostium of the three main hepatic veins of the recipient (RML) are used. On the other hand, venous return is reduced in these modalities due to a more pronounced constriction during the IVC clamping. Theoretically, the use of the ostium formed by the right and middle hepatic veins (RM) may limit IVC constriction during lateral clamping while providing a hepatic venous outflow tract with no anatomical restrictions. The aim of this study is to compare, in fresh human cadavers, the transversal area of the IVC during the partial clamping for performing ME, RML and RM modalities of hepatic venous outflow tract reconstruction in piggyback liver transplantation. (AU)
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