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Study of degradation diethylstilbestrol (des ) and bisphenol a ( BFA) in effluents in the Greater ABC region (SP ) by HPLC -FL using fungi

Grant number: 16/05642-9
Support type:Regular Research Grants
Duration: April 01, 2018 - September 30, 2020
Field of knowledge:Health Sciences - Collective Health - Public Health
Principal Investigator:Elizabete Campos de Lima
Grantee:Elizabete Campos de Lima
Home Institution: Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil


Contamination of water resources is one of the major environmental problems of our time, and the concern micropollutants - substances that appear in concentrations in order of µgL-1 and ngL-1 has increased significantly in recent years Among the substances which can be classified as micropollutants include the compounds with estrogenic activity such as of bisphenol A (BFA) and the synthetic estrogen diethylstilbestrol (DES). Endocrine disruptors with estrogenic activity are those that arouse most concern to health workers, as they are extremely biologically active and have a solid introduction into the environment. The removal of emerging pollutants through stabilization ponds - the leading technology in wastewater treatment in Brazil - shows variation in efficiency (Person et al, 2012.). Other processes for removing pollutants are emerging reverse osmosis, chemical oxidation, ozonolysis, and the other tooth. Procedures are expensive; they require many modifications to existing processing lines and therefore large financial investment, fact that leads to the impossibility installation thereof. However, the oxidation of pollutants arising by enzymes derived from microorganisms has been considered a novel and potentially effective technology for the removal of these substances in wastewater that will eventually be discharged into the environment. Scholars such as Cajthaml (2014) is already applying ligninolytic fungi to remove estrogens in samples; Gimenes (2011) used the Trametes villosa species for pentachlorophenol degradation, among others. Also observed is the application of these fungi in the degradation of textile dyes derived. (Balan & Miller, 2001) This study aims to determine, by high performance liquid chromatography precision with fluorescence detector (HPLC-DAD), the potential of BFA degradation and DES by basidiomycetes of Trametes and Pleurotus genera, called white decay fungi, whose lignolíticas enzymes have known oxidizing power (SALVI, 2011); and the concentration of the products of this degradation. They will be used to study water samples from Billings reservoir located in the Greater ABC region. (AU)