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Conventional ultrasound and color-flow and Power Doppler for the evaluation of canine mammary tumors

Grant number: 08/08180-0
Support Opportunities:Scholarships in Brazil - Doctorate
Start date: March 01, 2009
End date: December 31, 2010
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Reproduction
Principal Investigator:Wilter Ricardo Russiano Vicente
Grantee:Marcus Antônio Rossi Feliciano
Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

In veterinary medicine, the useful of the ultrasonographic exam in the evaluation of the breast tumors is very limited and presents low sensibility yet. This because there are not researches that demonstrate the relation of the imaging diagnosis findings with routine and conclusives techniques to the characterization of the malignancy in bitches and, how used in humans, the color Doppler mode utilization to formation of new vessels detection. The proposed research has how purpose to diagnosis the mammary neoplasms in bitches through conventional ultrasonographic exam and color Doppler mode. They will be used to the research 60 animals, distributed according with the ultrasonographic findings in three groups (growing in relation to the malignancy). They will be made physical, conventional ultrasonographic and with color Doppler mode exams, macroscopic and microscopic evaluation in the neoplasms, quantification of the blood levels of progesterone, estrogen and prolactin, histologic evaluation through collected sample by puncture and will be estimated vascular endothelial growth factor (VEGF) levels. By this way, it was suggested that from obtained datas will be possible to characterize the malignancy of non invasive way of the mammary tumors in bitches, evaluating the tissue characteristics and the presence of formation of new vessels (to determine the sensibility of the ultrasonographic exam). (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
M.A.R. FELICIANO; A.S. SILVA; R.V.R. PEIXOTO; P.D. GALERA; W.R.R. VICENTE. Estudo clínico, histopatológico e imunoistoquímico de neoplasias mamárias em cadelas. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 64, n. 5, p. 1094-1100, . (08/08180-0)
FELICIANO, M. A. R.; VICENTE, W. R. R.; SILVA, M. A. M.. Conventional and Doppler ultrasound for the differentiation of benign and malignant canine mammary tumours. JOURNAL OF SMALL ANIMAL PRACTICE, v. 53, n. 6, p. 332-337, . (08/08180-0)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
FELICIANO, Marcus Antônio Rossi. Ultrassonografia convencional e modo Doppler em cores e Power na avaliação da neoplasia mamária em cadelas. 2010. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.