EXPERIMENTAL BPF : Reviews ventilation, gas exchange and hemodynamic

• Grant number: 09/04610-2
• Support Opportunities: Scholarships in Brazil - Master
• Start date: September 01, 2009
• End date: September 30, 2010
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Antonio Luis Eiras Falcão
• Grantee: Douglas Guimaraes de Oliveira
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The bronchopleural fistula (BPF) is a complication that takes to higher hospital mortality, potentially severe when associated with mechanical ventilation (MV). Thus, the purpose of this study is to evaluate ventilatory, hemodynamics and gasometrics parameters in a surgical induction of experimental BPF mechanically ventilated pigs. Were studied six pigs (25kg) underwent endotracheal intubation (ET) under MV and hemodynamically monitored with Swan -Ganz catheter. Between ET and the circuit was connected to the MV capnography sensor. Ventilatory, hemodynamics and gasometrics parameters datas were recorded before surgical act and after induction of BPF with debt exceeding 50% of the inspired volume.