Peptides with anti-tumor activity against murine melanoma (B16F10-Nex2.1) and human melanoma(A2058) based on the structure of CDRs (VH1, 2 and 3, VL1, 2 and 3) from mAb AC-1001 and mechanisms of cell death

• Grant number: 10/16447-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2010
• End date: November 30, 2012
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal Investigator: Luiz Rodolpho Raja Gabaglia Travassos
• Grantee: Aline Nogueira Rabaça
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

RABACA, ALINE N.; ARRUDA, DENISE C.; FIGUEIREDO, CARLOS R.; MASSAOKA, MARIANA H.; FARIAS, CAMYLA F.; TADA, DAYANE B.; MAIA, VERA C.; SILVA JUNIOR, PEDRO I.; GIROLA, NATALIA; REAL, FERNANDO; et al. AC-1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model. FEBS OPEN BIO, v. 6, n. 9, p. 885-901, SEP 2016. (10/16447-6)