| Grant number: | 11/00054-8 |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |
| Start date: | March 01, 2011 |
| End date: | December 31, 2011 |
| Field of knowledge: | Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine |
| Principal Investigator: | Alessandra Marnie Martins Gomes de Castro |
| Grantee: | Katarina Baumgartner Yamada |
| Host Institution: | Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
Abstract Porcine Circovirus-2 (PCV2) is responsible for swine circovirose that includes several clinical conditions. The impact is big on pig farms, as it affects animal performance and therefore the productivity of the farm. The wide spread of the agent in the swine population has raised the need to search for new biological models allowing the study of the dynamics of disease. The mouse is widely used as animal model for several diseases in different animal species, including the pig. Some recent studies have shown that this model allows the viral replication, while others failed to demonstrate infection, indicating that PCV2 infection in mice is still controversial. The project aims to quantify the PCV2 DNA in samples from tissue and feces of mice of strain CH3 / RockefellerPCV2b infected at 21 days old. | |
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