Influence of verapamil on the oxcarbazepine enantiomers and 10-hydroxycarbazepine pharmacokinetics and their relationships to cerebral perfusion in healthy volunteers

• Grant number: 11/06887-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: September 01, 2011
• End date: September 01, 2014
• Field of knowledge: Biological Sciences - Pharmacology - Clinical Pharmacology
• Principal Investigator: Vera Lúcia Lanchote
• Grantee: Natalícia de Jesus Antunes
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated scholarship(s): 12/18175-9 - Correlation between cerebral perfusion and pharmacokinetics of OXC and its metabolite 10-hidroxicarbazepina enantiomers in the plasma of healthy volunteers using non-linear hierarchical models, BE.EP.DR

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ANTUNES, NATALICIA DE JESUS; VAN DIJKMAN, SVEN C.; LANCHOTE, VERA LUCIA; WICHERT-ANA, LAURO; COELHO, EDUARDO BARBOSA; ALEXANDRE JUNIOR, VERIANO; TAKAYANAGUI, OSVALDO MASSAITI; TOZATTO, EDUARDO; VAN HASSELT, J. G. COEN; DELLA PASQUA, OSCAR. Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects. European Journal of Pharmaceutical Sciences, v. 109, p. 8-pg., 2017-11-15. (11/06887-1, 12/18175-9)

ANTUNES, NATALICIA DE JESUS; VAN DIJKMAN, SVEN C.; LANCHOTE, VERA LUCIA; WICHERT-ANA, LAURO; COELHO, EDUARDO BARBOSA; ALEXANDRE JUNIOR, VERIANO; TAKAYANAGUI, OSVALDO MASSAITI; TOZATTO, EDUARDO; VAN HASSELT, J. G. COEN; DELLA PASQUA, OSCAR. Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects. European Journal of Pharmaceutical Sciences, v. 109, n. S, SI, p. S116-S123, NOV 15 2017. (12/18175-9, 11/06887-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ANTUNES, Natalícia de Jesus. Influence of verapamil on the pharmacokinetics and cerebral perfusion of oxcarbazepine and the enantiomers of its metabolite 10- hydroxycarbazepine in healthy volunteers. 2014. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (PCARP/BC) Ribeirão Preto.