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Comparing exercise training and CPAP treatment in patients with heart failure and sleep apnea

Grant number: 11/51492-5
Support Opportunities:Scholarships in Brazil - Post-Doctoral
Start date: December 01, 2011
End date: November 30, 2013
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Lia Rita Azeredo Bittencourt
Grantee:Denise Maria Servantes
Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

Introduction. Heart failure is the result of primary ventricular dysfunction followed by neurohormorais changes, distribution of cardiac output, peripheral circulation, the skeletal and respiratory muscles, which determine their clinical and prognosis. Despite the advancement in treatment, morbidity and mortality remain high. Physical training appears as a teapeutic strategy, because most of its beneficial effects is by inducing changes in peripheral physiological changes resulting from heart failure. Associated factors that may contribute to its progression and worse prognosis, now beginning to be studied, such as sleep apnea, the diagnosis provides important prognostic information and a potential therapeutic option for these patients. Objectives. Demonstrate the benefits of physical training for patients with heart failure and sleep apnea, and compare treatment with CPAP alone and associated with the exercise program. Will also be assessed risk and adherence to physical training. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SERVANTES, DENISE MARIA; JAVAHERI, SHAHROKH; PELISSARI KRAVCHYCHYN, ANA CLAUDIA; STORTI, LUCIANA JULIO; ALMEIDA, DIRCEU RODRIGUES; DE MELLO, MARCO TULIO; CINTRA, FATIMA DUMAS; TUFIK, SERGIO; BITTENCOURT, LIA. Effects of Exercise Training and CPAP in Patients With Heart Failure and OSA A Preliminary Study. CHEST, v. 154, n. 4, p. 808-817, . (11/51492-5)