| Grant number: | 12/09274-3 |
| Support Opportunities: | Scholarships in Brazil - Master |
| Start date: | September 01, 2012 |
| End date: | May 31, 2014 |
| Field of knowledge: | Health Sciences - Physical Education |
| Principal Investigator: | Carlos Ugrinowitsch |
| Grantee: | Felipe Cassaro Vechin |
| Host Institution: | Escola de Educação Física e Esporte (EEFE). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
Abstract The American College of Sports Medicine has been recommending resistance training (RT) to improve and maintenance of elderly healthy, main to decrease atrophy process. A reduction in type II fibers, decrease the ability of generate force quickly (i.e. power and strength), consequently, the capacity to do daily activities is decreased (i.e. upstairs, stand up from chair, etc) while the risk of falls increased. However, to sedentary or people with some diseases, the hypertrophy training can be weary or even contraindicated because of high loads. A reduction in the volume of training (series x repetitions x loads) can reduce risks of cardiovascular and muscle injury and be interesting to elderly people. Therefore, since the last decade, studies have been showing that RT with low load and vascular occlusion (20 - 50%-1RM) induce hypertrophy and strength gains as high intensity RT. Thus, RT with vascular occlusion might be one alternative to promote type II fibers hypertrophy with a lower mechanic stress. The aim of this study is understand how molecular pathways of degradation and synthesis protein occur after acute and chronic RT with vascular occlusion in elderly people. Our hypothesis is that synthesis protein pathways will improve, as degradation pathways will suffer a reduction in their expressions. | |
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