Addition effect of l-carnitine and acetyl-l-carnitine on sperm viability in cooled equine semen

• Grant number: 12/11658-4
• Support Opportunities: Scholarships in Brazil - Master
• Start date: September 01, 2012
• End date: June 30, 2014
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Reproduction
• Principal Investigator: José Antonio Dell'Aqua Junior
• Grantee: Fernando Paixão Lisboa
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

Over the years, technology for cooling semen has developed. However, despite progress, pregnancy rates are still variable relates to variable semen quality of stallions. As an alternative to this situation, have been studied the addition of antioxidants to cooling extenders. The intention is to reduce membrane damage caused by lipid peroxidation, enhancing sperm viability. The aim of this study is to evaluate the effect of addition of L-carnitine and acetyl-L-carnitine on sperm viability in cooling equine semen at 5° C for 48 hours. These compounds show potential to minimize the deleterious effects caused by the cooling of equine semen as well as stimulating the metabolic pathways responsible for energy production in sperm. However, it is necessary the development of protocols for the addition of these components, plus a complete analysis of the sperm cell, to evaluate its effects on semen characteristics of stallions. (AU)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

LISBOA, Fernando Paixão. Efeito da adição da L-carnitina e acetil-L-carnitina sobre a viabilidade espermática na refrigeração do sêmen equino. 2014. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Medicina Veterinária e Zootecnia. Botucatu Botucatu.