Gangliogliomas: a retrospective study about magnetic resonance imaging findings in a series of cases in Clinical Hospital of Unicamp

• Grant number: 12/20689-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2012
• End date: October 31, 2013
• Field of knowledge: Health Sciences - Medicine - Medical Radiology
• Principal Investigator: Fabiano Reis
• Grantee: Vinícius Trindade Gonçalves
• Host Institution: Hospital de Clínicas (HC). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Gangliogliomas are the most common mixed neuronal-glial tumor of the Central Nervous System (CNS). They comprise about 1% of all brain tumors, affecting mainly children and young adults and are usually associated with medically refractory epilepsy. In general, gangliogliomas are classified as low-grade, slow-growing tumors, with good prognosis after complete resection. However, complete resection may be impossible and ganglioglioma eventually develops anaplastic features, which are classified as WHO (World Health Organization) grade III tumors. This study aims to analyze the characteristics of magnetic resonance image (MRI) and possible clinical and pathological correlation of a series of patients with histological diagnosis of ganglioglioma, from a university hospital: the Clinical Hospital of State University of Campinas (UNICAMP).(AU)