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Correlation between digestion and hormones hemoncose (Haemonchus contortus and H. placei) in experimental cattle

Grant number: 14/12104-8
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2014
Effective date (End): July 31, 2015
Field of knowledge:Biological Sciences - Parasitology - Helminthology of Parasites
Principal Investigator:Alvimar José da Costa
Grantee:Débora Siniscalchi
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

Parasitic infections caused by gastrointestinal nematodes undertake animal productivity. Among these species, the genus Haemonchus are considered the most pathogenic, affecting mainly young animals have not acquired resistance. These infections cause a reduction in food consumption, which may be related to anemia, abdominal pain generated by the action of parasites and even the hormonal changes, especially gastrin. The objective of the study is to evaluate the levels of secretion of hormones related to digestion in calves with Haemonchus primoinfectados. H. contortus and placei. This will be used 10 calves, created and maintained without contact with helminths, as follows: GI-not two calves inoculated GII-four calves inoculated with H. contortus L3 and GIII-four calves infected with L3 of H. placei. Each receive bovine L3 10,000, according to the experimental group in a single dose. Fecal examinations are performed daily. Will be weekly harvested until 42 days after inoculation blood samples for hormone analyzes. The measurements are performed by using enzyme immunoassay kits specific diagnosis, for gastrin and gastric inhibitory peptide hormones. From the results obtained, properly analyzed statistically, the appropriate inferences be drawn.