Relation between the body fat and the presence of organochlorine agrochemicals residue in the milk from Santa Casa Hospital bank female donors - Limeira, São Paulo State

• Grant number: 14/21862-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: February 01, 2015
• End date: November 30, 2015
• Field of knowledge: Health Sciences - Collective Health - Public Health
• Principal Investigator: Julicristie Machado de Oliveira
• Grantee: Jéssica Lancellotti de Souza
• Host Institution: Faculdade de Ciências Aplicadas (FCA). Universidade Estadual de Campinas (UNICAMP). Limeira , SP, Brazil

Abstract

Human milk is the recomended food for newborns, because it has macronutrients in the adequate proportion, and vitamins/minerals of high bioavailability and digestibility. Exclusive breastfeeding is recommended for up to six months of age. Organochlorine agrochemicals are soluble in fat - they have a great affinity for fat, therefore - and build up in the mother's adipose tissue. The mother's exposure to agrochemicals in cities happens mainly through diet. During the milk-production process by the mammary glands, the mother's energy stocks are mobilized - mainly from the adipose tissue. Due to that, the residue from agrochemicals is excreted along with the essential components for the newborn's nutrition. The intense use of agrochemicals generates a vulnerable situation, especially for newborns whose vital systems are still immature. This project seeks to establish a correlation between the mother's body fat percentage and the amount of residue from agrochemicals excreted in human milk. Samples from 100 female donors will be collected at the Milk Bank from Limeira's Santa Casa de Misericórdia - São Paulo State. Social-demographic and anthropometric data will be collected through the application of a questionnaire and a nutritional assessment. Milk samples will be analyzed through CG, CG/MS, and Ekomilk.