Sensitive label free detection of disease markers using electrochemical immittance

• Grant number: 15/15682-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2015
• End date: August 31, 2016
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Paulo Roberto Bueno
• Grantee: Inácio José Galego Cassimiro
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated research grant: 12/22820-7 - The sensitive label free detection of disease markers using electrochemical immittance, AP.TEM

Abstract

The electrochemical immittance is a concept recently developed by São Paulo State University (UNESP) and Oxford University with some joint patents deposited and some academic publications. It allows ultrasensitive label free detection of clinically important targets and binding affinity. Within this platform a biofunctionalized transducer surfaces (in microarray platform or not) can be generated using specific surface chemistries and binding moieties to target specific clinically important proteins associated with diseases and pathological disorders. The main purpose of this project is to continue to develop the concept and explore its functionality for clinical important markers using this concept to explore its applicability in UK and Brazilian patients. (AU)