Effects of trendelenburg posicition associated with pneumoperitoneum on intraocular pressure in cats

• Grant number: 15/11012-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2015
• End date: August 31, 2016
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Cristiane dos Santos Honsho
• Grantee: Letícia Dominici Arroyo
• Host Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil

Abstract

The purpose of this study is to assess the influence of CO2 pneumoperitoneum associated with Trendelenburg positioning on IOPs. For this, we used six cats of both sexes, clinically healthy, weighing 3.5 kg. The animals will be induced to anesthesia with isoflurane via induction's chamber, immediately be intubated and maintained with the same anesthetic agent. Intraocular pressure (IOP) will be measured by tonometry, moreover, will be assessed and recorded values of heart rate and respiratory rate, systolic, mean and diastolic blood pressure, rectal temperature, hydrogen potential in arterial blood (pHa) partial pressure of oxygen in arterial blood (PaO2), partial pressure of carbon dioxide in arterial blood (PaCO2), arterial oxygen saturation (SaO2), bicarbonate ion (HCO 3), base deficit (DEB). Data will be collected at times: T0 - baseline; (TAINS) immediatly before abdominal insufflation; (TI5) 5 min after abdominal insufflation, TI15 and TI30 understand 15 and 30 minutes after TIS, respectively. The results will be tested using the Shapiro-Wilk normality, when normally distributed will be employed analysis of variance (ANOVA) for repeated measures and Bonferroni's complementary analysis and variables with normal distribution are compared with the Wilcoxon test. The Pearson correlation test will be used to correlate the PaCO2, mean arterial pressure and positioning with the PO. The significance level is 5%.