Chemical and ecological study of microorganisms associated with the symbiosis Cecropia-Azteca

• Grant number: 15/26349-5
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: March 01, 2016
• End date: January 12, 2021
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Mônica Tallarico Pupo
• Grantee: Taise Tomie Hebihara Fukuda
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated scholarship(s): 17/17305-0 - Understanding the bacterial symbiosis in Cecropia-Azteca system using chemical and genetic tools, BE.EP.DD

Abstract

This project aims to study the microbial community associated with the symbiosis between myrmecophytes of the genus Cecropia and ants of the genus Azteca, as well as the secondary metabolites produced in this interaction. Microorganisms associated with social insects have been extensively studied as sources of new chemical structures with antimicrobial activity and there are no studies in the literature of microorganisms associated with this Cecropia-Azteca interaction. The microorganisms isolated will be tested through inhibition assays against entomopathogenic fungi and human pathogens. The isolated and identified products will also be subjected to biological assays for possible correlation with their ecological function. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FUKUDA, TAISE T. H.; CASSILLY, CHELSI D.; GERDT, JOSEPH P.; HENKE, MATTHEW T.; HELFRICH, ERIC J. N.; MEVERS, EMILY. Research Tales from the Clardy Laboratory: Function-Driven Natural Product Discovery. Journal of Natural Products, v. 83, n. 3, SI, p. 744-755, MAR 27 2020. (15/26349-5, 13/50954-0)

FUKUDA, TAISE T. H.; PEREIRA, CAMILA F.; MELO, WEILAN G. P.; MENEGATTI, CARLA; ANDRADE, PAULO H. M.; GROPPO, MILTON; LACAVA, PAULO T.; CURRIE, CAMERON R.; PUPO, MONICA T.. Insights Into the Ecological Role of Pseudomonas spp. in an Ant-plant Symbiosis. FRONTIERS IN MICROBIOLOGY, v. 12, FEB 1 2021. (17/17305-0, 16/26230-0, 16/15576-3, 13/50954-0, 19/19099-3, 15/26349-5, 15/01001-6)

FUKUDA, TAISE T. H.; CASSILLY, CHELSI D.; GERDT, JOSEPH P.; HENKE, MATTHEW T.; HELFRICH, ERIC J. N.; MEVERS, EMILY. Research Tales from the Clardy Laboratory: Function-Driven Natural Product Discovery. Journal of Natural Products, v. 83, n. 3, p. 12-pg., 2020-03-27. (13/50954-0, 15/26349-5)

FUKUDA, TAISE T. H.; HELFRICH, ERIC J. N.; MEYERS, EMILY; MELO, WEILAN G. P.; VAN ARNAM, ETHAN B.; ANDES, DAVID R.; CURRIE, CAMERON R.; PUPO, MONICA T.; CLARDY, JON. Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis. ACS CENTRAL SCIENCE, v. 7, n. 2, p. 292-299, FEB 24 2021. (17/17305-0, 15/26349-5, 15/01001-6, 13/50954-0)

MENEGATTI, CARLA; FUKUDA, TAISE T. H.; PUPO, MONICA T.. Chemical Ecology in Insect-microbe Interactions in the Neotropics. Planta Medica, v. 87, n. 01/02, p. 38-48, FEB 2021. (16/15576-3, 13/07600-3, 13/50954-0, 15/26349-5)

BATISTA, JULIANA H.; LEAL, FERNANDA C.; FUKUDA, TAISE T. H.; ALCOFORADO DINIZ, JULIANA; ALMEIDA, FAUSTO; PUPO, MONICA T.; DA SILVA NETO, JOSE F.. Interplay between two quorum sensing-regulated pathways, violacein biosynthesis and VacJ/Yrb, dictates outer membrane vesicle biogenesis in Chromobacterium violaceum. ENVIRONMENTAL MICROBIOLOGY, v. 22, n. 6, MAY 2020. (18/01388-6, 18/25445-9, 13/50954-0, 15/26349-5)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

FUKUDA, Taise Tomie Hebihara. Understanding the ant-bacteria symbiosis using chemical and genetic tools. 2022. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (PCARP/BC) Ribeirão Preto.