Synthesis and functionalization of vinyl iodide sulfoxides

• Grant number: 16/05260-9
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: August 01, 2016
• End date: July 31, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Helio Alexandre Stefani
• Grantee: Frederico Bernardes de Souza
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 12/00424-2 - Synthesis of small libraries using potassium Organotrifluoroborates in Suzuki-Miyaura reactions, AP.TEM

Abstract

The project has as its main theme the use of potassium salts organotrifluoroboratos (nucleophilic species) for the development of type Suzuki-Miyaura reactions between these salts and iodide vinyl sulfoxides (electrophiles), catalyzed by a transition metal complex to promote the formation of sp2-sp2 bonds, sp-sp 2, sp-sp to obtain compounds of importance for synthetic view. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SOUZA, FREDERICO B.; VASCONCELOS, STANLEY N. S.; REIS, JOEL S.; PIMENTA, DANIEL C.; STEFANI, HELIO. Synthesis and functionalization of N-sulfinyl imines: Sonogashira reaction and copper-catalyzed azide-alkyne cycloaddition. Tetrahedron Letters, v. 58, n. 11, p. 1057-1060, MAR 15 2017. (12/00424-2, 16/05260-9)