Evaluation of blood samples stability after transportation in a multicenter study in South America

• Grant number: 15/18876-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2016
• End date: May 31, 2017
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Principal Investigator: Augusto César Ferreira de Moraes
• Grantee: Raphael Assali Serruya
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The aim of this study is to evaluate biomarker stability (hematologic values, lipid profile, nutritional and metabolic status, inflammatory and anti-inflammatory markers) on blood samples from participants depending on time, temperature during storage and transportation to central laboratory in São Paulo. This multicenter study will analyze children and adolescents between 3 and 17 years old from São Paulo (Brazil) and other six South American cities: Teresina (Brazil), Buenos Aires (Argentina), Santiago (Chile), Montevideo (Uruguay), Lima (Peru) and Medellín (Colombia). The study sample will consist of 18 children of each age group (preschoolers, schoolers and adolescents) in each city. After standardized blood collection, a third of the samples will be fractionated, one part being analyzed in the city of origin and the other being sent to the central laboratory in São Paulo, by a specialized company in transportation of biological material, for analysis. The agreement between results obtained in the city of origin of these samples and in the central laboratory will be calculated using intraclass correlation coefficient, supplemented with Bland-Altman plots.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LOPEZ, GRACIELA; SERRUYA, RAPHAEL ASSALI; BARCHUK, MAGALI; GAITAN-CHARRY, DIEGO; TORRES-LEAL, FRANCISCO LEONARDO; MORENO, LUIS ALBERTO; DELGADO, CARLOS ALBERTO; CARVALHO, HERACLITO BARBOSA; FERREIRA DE MORAES, AUGUSTO CESAR; BERG, GABRIELA. Sampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study. SCIENTIFIC REPORTS, v. 10, n. 1, JAN 20 2020. (17/20317-0, 15/11406-3, 15/18876-5, 14/11468-6, 19/02617-1)