Itramolecular Cycloaddition [2+2] Reactions Employing D-Glucal

• Grant number: 18/10108-7
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: November 01, 2018
• End date: December 31, 2020
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Helio Alexandre Stefani
• Grantee: Antonio Augusto Soares Paulino
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The main focus of the project is the use of 3,4,6-tri-O-acetyl-D-glucal for transformations involving intermolecular cycloaddition [2+2] reactions. It is also intended to evaluate the biological activity of the compounds prepared (e.g. antifungal, anticancer and anti-inflammatory activity).

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SOARES-PAULINO, ANTONIO AUGUSTO; STEFANI, HELIO A.. Synthesis of Diverse C2-Glyco-Acyl Azides and -Ureas by Palladium-Catalyzed Carbonylation Coupling of 2-Iodoglycals. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, v. 2020, n. 25, JUN 2020. (14/50316-7, 18/10108-7, 17/24821-4)