Synthesis and interaction of metal oxide nanostructures and topological insulating materials with biomolecules

• Grant number: 19/01425-1
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: March 01, 2019
• End date: February 28, 2023
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Principal Investigator: Iseli Lourenço Nantes Cardoso
• Grantee: Julia Delatorre Bronzato
• Host Institution: Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil
• Associated research grant: 17/02317-2 - Interfaces in materials: electronic, magnetic, structural and transport properties, AP.TEM
• Associated scholarship(s): 19/22092-0 - Spin selective electron transport between semiconductors and cytochrome C, BE.EP.DD

Abstract

Biomolecules are useful for the green synthesis, stabilization, and mediation of the redox processes of metallic nanostructures, oxides, and materials with properties of topological insulators. Previous studies conducted by our group has shown two types of interactions of biomolecules with nanostructures. The redox center of cytochrome C, ferroprotoporphyrin IX, can act as electron acceptor of semiconductors such as TiO2, Fe3O4, and ZnO photoexcited. Also, ²-glycosidases enzymes are efficient as the AgX crystalline growth targeting template, X being a halide as Cl, I and Br, without loss of enzymatic activity. Also, we have observed that tomato extracts (Solanum lycopersicum; Solanaceae) produce gold nanoparticles together with nanostructured magnetite, only with the addition of gold salt. We believe that the tomato ferritin provides the material for the synthesis of magnetite with some catalytic contribution of the gold nanoparticles. In this project, the objectives will be to characterize the interaction and redox processes between cytochrome C and porphyrins with Fe3O4 and ZnO modulated by pH, isotopic replacement of water, and structural organization of iron oxide. Also, to characterize the formation process of nanocrystalline magnetite by ferritin with gold nanoparticle mediation and to synthesize and characterize the synthesis of Bi2Se3 using different proteins such as ²-glycosidases and other proteins and peptides with promising structures. All these processes are related to the phenomena of interfaces involving hydration, zeta potential, interactions of organic molecules with inorganic surfaces, crystalline growth, and organization, and electron transfer. Surface interactions with ZnO and topological insulators are feasible from a theoretical approach through collaboration with other researchers involved in the project. The project will result in publications in impact journals and possibly patents. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BRONZATO, JULIA D.; TOFANELLO, ARYANE; OLIVEIRA, MARTHA T.; BETTINI, JEFFERSON; BRITO, ADRIANNE M. M.; COSTA, SILGIA A.; COSTA, SIRLENE M.; LANFREDI, ALEXANDRE J. C.; NASCIMENTO, OTACIRO R.; NANTES-CARDOSO, ISELI L.. Virucidal, photocatalytic and chiromagnetic cobalt oxide quantum dots. Applied Surface Science, v. 576, n. A, FEB 1 2022. (19/01425-1, 17/02317-2)

TOFANELLO, ARYANE; BRONZATO, JULIA D.; RETTORI, CARLOS; NASCIMENTO, OTACIRO R.; NANTES-CARDOSO, ISELI L.. Conversion of ferritin ferrihydrite core to magnetite by gold ions binding and the derived nanoparticle formation. JOURNAL OF NANOSTRUCTURE IN CHEMISTRY, JUL 2021. (19/01425-1, 17/02317-2)

MENEZES, LUCIVALDO R.; SOMBRIO, GUILHERME; COSTA, CLAUDIA A.; BRONZATO, JULIA D.; RODRIGUES, TIAGO; SOUZA, JOSE A.; NANTES-CARDOSO, ISELI L.. Nanostructured Hematite Decorated with Gold Nanoparticles for Functionalization and Biocompatibility. PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, v. 217, n. 5, p. 10-pg., 2019-11-13. (19/01425-1, 17/02317-2, 19/01785-8)