Development of a catalytic system compatible with olefins and aromatic systems for oxidation of C-H bonds

• Grant number: 20/11568-1
• Support Opportunities: Scholarships in Brazil - Master
• Start date: October 01, 2020
• End date: December 31, 2022
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Emílio Carlos de Lucca Júnior
• Grantee: Kelita Angelo de Paula
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 18/04837-6 - Oxidation of aliphatic C-H bonds catalyzed by transition metals, AP.JP

Abstract

The traditional applied methods for construction and growth of complexity in organic molecules rely on the manipulation of functional groups which are considered reactive, such as, carbonyls, alcohols, amines, and halogenated groups. In contrast, nature routinely uses methods to direct oxidation of C-H bonds, installing oxidized functionalities directly onto complex hydrocarbon framework, without pre-functionalization. Thus, the development of catalytic methods for the oxidation of C-H bonds presents a series of advantages, such as, the increase of synthetic efficiency. Despite the advances made, in order to the C-H bond oxidation reaches its full potential, a series of challenges still have to be overcome and, therefore, we propose to investigate catalytic systems to develop reactions compatible with electron-rich functional groups, i.e., olefins and aromatic rings. (AU)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

PAULA, Kelita Angelo de. Oxidative reactions of C-H bonds in nitrogenous compounds in the presence of a iron-ferro catalyst. 2023. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Instituto de Química Campinas, SP.