Resistance and susceptibility in Congenital Zika Virus Syndrome

• Grant number: 21/01717-2
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: April 01, 2021
• End date: January 31, 2023
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal Investigator: Jean Pierre Schatzmann Peron
• Grantee: Patrick da Silva
• Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 17/26170-0 - Neuroimmunology in experimental models of Autoimmune Encephalomyelitis and Congenital Zika Syndrome: physiopathogenesis, susceptibility, cellular therapy, vaccination, AP.TEM

Abstract

The project aims to search for and understand genes that confer resistance or susceptibility to Congenital ZIKV Syndrome, using both samples from women who have had affected babies and experimental models. Sequencing screenings will be carried out, in addition to in vivo validation experiments in a murine model. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

POLONIO, CAROLINA M.; DA SILVA, PATRICK; RUSSO, FABIELE B.; HYPPOLITO, BRENDO R. N.; ZANLUQUI, NAGELA G.; BENAZZATO, CECILIA; BELTRAO-BRAGA, PATRICIA C. B.; MUXEL, SANDRA M.; PERON, JEAN PIERRE S.. microRNAs Control Antiviral Immune Response, Cell Death and Chemotaxis Pathways in Human Neuronal Precursor Cells (NPCs) during Zika Virus Infection. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 18, p. 19-pg., 2022-09-01. (20/06145-4, 17/11828-0, 17/26170-0, 21/01717-2, 18/16748-8, 17/22504-1, 22/00291-4, 16/07371-2, 19/13731-0)