UV-based advanced oxidation processes for the treatment of complex real matrices: analytical, ecotoxicological and cytotoxicity evaluation

• Grant number: 21/13314-0
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: May 26, 2022
• End date: May 25, 2023
• Field of knowledge: Engineering - Sanitary Engineering - Water Supply and Wastewater Treatment
• Principal Investigator: Marcos Roberto de Vasconcelos Lanza
• Grantee: Isaac José Sánchez Montes
• Supervisor: Mohamed Gamal El-Din
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Institution abroad: University of Alberta, Canada
• Associated to the scholarship: 20/07351-7 - Advanced oxidation processes based on the in situ activation of oxidants via UVC and solar radiation for the simultaneous elimination of microcontaminants and pathogens, BP.PD

Abstract

Considering: (i) the level of excellence of the work developed by Dr. Gamal El-Din's group at the University of Alberta, as well as his extensive experience in fundamental research on advanced oxidation processes (AOPs) and (ii) the studies performed at GPEA/IQSC related to the original project on the removal of organic and biological contaminants by the photolysis of oxidants, this project focuses on performing a comprehensive research of the activation of different oxidants (O3, H2O2, S2O82-, HSO5- and ClO-) under distinct UV irradiation sources (UVC, VUV, UV-LEDs and solar radiation) to treat complex real matrices containing a mixture of representative organic pollutants at very low concentration (100 µg L-1 each). In this study, 13 micropollutants (MPs) with significant differences regarding their chemical structures and their potential toxicity against aquatic ecosystems will be investigated simultaneously: 6 pharmaceuticals, 2 personal care products, 3 pesticides and 2 perfluorinated compounds. The efficiency of these processes will be compared in terms of MPs degradation rates, oxidant consumption, generation of by-products and energy consumption. Finally, the environmental compatibility of the treated matrices will be investigated by ecotoxicity tests using representative microorganisms of producers (green algae Chlorella vulgaris) and primary consumers (Daphnia magna), as well as by cytotoxicity assays in murine and human cell lines by quantitative polymerase chain reaction (qPCR). (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SANTOS, GESSICA O. S.; GOULART, LORENA A.; CORDEIRO-JUNIOR, PAULO J. M.; SANCHEZ-MONTES, ISAAC; LANZA, MARCOS R., V. Pharmaceutical contaminants: Ecotoxicological aspects and recent advances in oxidation technologies for their removal in aqueous matrices. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 10, n. 6, p. 31-pg., 2022-11-16. (16/08760-2, 17/10118-0, 20/02743-4, 21/13314-0, 20/07351-7, 16/19612-4, 22/03386-6)

SANCHEZ-MONTES, ISAAC; SANTOS, GESSICA O. S.; DOS SANTOS, ALEXSANDRO J.; FERNANDES, CARLOS H. M.; SOUTO, ROBSON S.; CHELME-AYALA, PAMELA; EL-DIN, MOHAMED GAMAL; LANZA, MARCOS R. V.. Toxicological aspect of water treated by chlorine-based advanced oxidation processes: A review. Science of The Total Environment, v. 878, p. 20-pg., 2023-06-20. (14/50945-4, 20/02743-4, 22/03386-6, 17/10118-0, 20/07351-7, 21/13314-0, 19/20634-0, 21/08701-4)