Assessment of the Performance of Adult and Fetal Magnetocardiography System based on Optically Pumped Magnetometers

• Grant number: 23/11948-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: October 01, 2023
• End date: September 30, 2025
• Field of knowledge: Biological Sciences - Biophysics
• Principal Investigator: Oswaldo Baffa Filho
• Grantee: Débora Martins de Souza
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Magnetocardiography (MCG) is a non-invasive technique that records the magnetic fields generated by the electrical activity of the heart. MCG has gained wide acceptance because it provides valuable information about cardiac function, allowing for early detection of heart problems, risk assessment, and customization of treatment for patients. However, cardiac magnetic fields have low amplitude; thus, require the use of highly sensitive sensors and magnetic shields to attenuate external magnetic interference. Therefore, the adoption of the MCG was limited by the high cost of the Superconducting Quantum Interference Devices (SQUIDs) and the magnetically shielded rooms. Recently, a new technology called Optically Pumped Magnetometers (OPMs) has emerged with the potential of replacing SQUIDs, as the OPMs can achieve the same sensibility at a reduced cost and size, and without the need for cryogenics. In addition, OPMs can be used within person-sized cylindrical magnetic shields. These factors have made the MCG more affordable and accessible. This project aims to evaluate the performance of a system of OPMs within a person-sized shield for MCG measurements, which will be collected from individuals of different age groups, including fetuses, who may either exhibit normal health or have been diagnosed with arrhythmias. The study will provide comprehensive insights into both the MCG technique and this new methodology, enabling us to contribute to its enhancement in future studies. Our goal is to make the MCG a more accessible alternative for the identification and evaluation of arrhythmias and other cardiac pathologies, ultimately enhancing patient care.