Evaluation of the mechanisms of humoral and cellular immunity in response to vaccines and antiviral drugs.

• Grant number: 24/06260-9
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: June 01, 2024
• End date: May 31, 2026
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Durvanei Augusto Maria
• Grantee: Isabela Mancini Martins
• Host Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 21/11946-9 - Technological Innovation Platform for Health Emergencies, AP.CCD

Abstract

Elucidate mechanisms of action and cellular signaling involved in the production of neutralizing antibodies and cellular immunity, mediated by T lymphocytes and the profile of pro- and anti-inflammatory cytokines. Development of a research platform for pre-clinical trials on GLP, in rodents and non-rodents. Study of the physiopathogenesis of SARS-Cov-2 in animal models.Training in the guidance of scientific initiation students and postgraduate students.Critical interpretation of results and preparation of scientific works for publication in journals with a significant impact factor.