1-Iodine-D-Glucal Functionalization Using Organoboron Compounds via Carbonylative Coupling Reaction

• Grant number: 24/07240-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2024
• End date: July 31, 2025
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Helio Alexandre Stefani
• Grantee: Eurípedes de Aguiar
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The project's main focus is the use of 1-iodoglucal and organoboron compounds in transformations involving carbonylative coupling reactions. It is also intended, when possible, to evaluate the biological activity of the prepared compounds (e.g. antifungal, anticancer and anti-inflammatory activity).