PREOPERATIVE AND POSTOPERATIVE AUTOHEMOTHERAPY APPLIED TO FEMALE DOGS UNDERGOING TOTAL UNILATERAL MASTECTOMY

• Grant number: 24/09050-5
• Support Opportunities: Scholarships in Brazil - Master
• Start date: October 01, 2024
• End date: September 30, 2026
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Silvio Henrique de Freitas
• Grantee: Pedro Gustavo Macedo Rihs
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil

Abstract

To evaluate the effectiveness of the association of a form of neoadjuvant therapy in the preoperative and postoperative period in unilateral radical mastectomy procedures in dogs, the technique of autohemotherapy (AHT) is applied. In which the administration of autologous blood intramuscularly is proposed, with the objective of organic stimulation of the patient's immune system, especially the Mononuclear phagocyte system, increasing the percentage of macrophages throughout the organism. Consequently, aiming at the potential in quality and reduction of healing time; reformulation of the established antibiotic therapy; and, possible reduction in the recurrence of neoplastic masses. Finally, it is expected that AHT can be associated with surgical procedures as a substitutive alternative to antibiotic therapy protocols, combined with prolonging the survival of animals with oncological diseases.