COMPARATIVE ANALYSIS OF CERVICAL ESOPHAGOGASTRIC ANASTOMOSIS USING MECHANICAL AND MANUAL SUTURE IN TWO PLANES IN PATIENTS UNDERGOING ESOPHAGEAL MUCOSECTOMY IN THE SURGICAL TREATMENT OF RECURRED ADVANCED IDIOPATHIC ACHALASIA OF THE ESOPHAGUS

• Grant number: 24/10046-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2024
• End date: June 30, 2025
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Jose Luis Braga de Aquino
• Grantee: Daniela Lalli de Freitas
• Host Institution: Escola de Ciências da Vida (ECV). Pontifícia Universidade Católica de Campinas (PUC-CAMP). Campinas , SP, Brazil

Abstract

Idiopathic achalasia of the esophagus is an inflammatory disease characterized by aperistalsis of the esophageal body and failure of the lower esophageal sphincter secondary to selective loss of function of inhibitory neurons of the myenteric plexus in response to unknown etiology. Therefore, patients who suffer from this motility disorder mainly present dysphagia and may develop malnutrition.Achalasia treatment does not aim to cure, but to improve the patients symptoms and quality of life. Among the surgical techniques available, mucosectomy with preservation of the muscular layer represent an alternative in the treatment of advanced idiopathic achalasia (grades III and IV in the radiological classification of Resende et al.). Although rare, the most frequent complications of mucosectomy are associated with cervical esophagogastric anastomosis, whether due to dehiscence or stenosis.This study aims to compare early and medium-term results of cervical esophagogastric anastomosis, with the mechanical and manual suture technique in two planes in 04 patients with advanced achalasia and relapse after previous cardiomyotomy, undergoing esophageal mucosectomy with preservation of the muscle layer.