Prospective, Observational, Multicenter Study to Evaluate Mortality, Infection Rate, and Number of Surgeries Related to the Use of Ventriculoperitoneal Shunts in Hydrocephalus Secondary to Infratentorial Tumors in Childhood and Adolescence

• Grant number: 24/16291-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2024
• End date: October 31, 2025
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Marcos Devanir Silva da Costa
• Grantee: Thaís Neri Andrade de Almeida Garcia
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

Pediatric brain tumors predominantly occur in the posterior fossa and are often associated with obstructive hydrocephalus, which can be managed through various procedures. However, there is no consensus in the literature regarding the most efficient and safe method, highlighting the need for multicenter and prospective research in this area. Ventriculoperitoneal shunting (VPS), despite being a technically straightforward procedure that can be performed by any trained neurosurgeon, is associated with complications such as infection, peritonitis, ascites, and epidural hematoma. Therefore, this study aims to conduct a multicenter and prospective investigation of patients treated with VPS to identify the mortality rate, infection rate, and the number of VPS revision surgeries, with the goal of determining its safety for patients