PREDICTORS OF POST-OPERATIVE ATRIAL FIBRILLATION IN PATIENTS UNDERGOING AORTIC VALVE REPLACEMENT

• Grant number: 25/19859-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2025
• End date: November 30, 2026
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Roney Orismar Sampaio
• Grantee: Letícia Marques de Abreu
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

Aortic stenosis (AS) is the most significant primary valve disease worldwide, and aortic valve replacement (AVR) surgery is frequently indicated in the population with severe AVR, as it is responsible for increasing overall survival.This condition currently has a high prevalence due to increased life expectancy, and the most common etiology isaortic degeneration, which primarily affects elderly patients (1). New-onset conduction disturbances are common after cardiac surgery-such as postoperative atrial tachyarrhythmias, especially atrial fibrillation-and occur inup to 50% of patients during the in-hospital period (8). Studies on predictors of AF in the postoperative period after AVR indicate that advanced age and mitral valve surgery increase the incidence of this arrhythmia, resulting inincreased morbidity and mortality (9-11) (16-18).In recent years, much research has focused on the prevention of AF after cardiac surgery; however, few studies have identified predictors of AF risk after aortic valve replacement (7).Therefore, the objective of this study is to identify predictors of atrial fibrillation after conventional aortic valve surgery in patients referred to the Valvular Heart Disease Outpatient Clinic of the Heart Institute of the Hospital das Clínicas de São Paulo, as well as to evaluate the long-term outcome and prognosis.This is an observational study that will include patients undergoing aortic valve replacement surgery admitted to the Valvular Heart Disease Outpatient Clinic of the Heart Institute of the Hospital das Clínicas de São Paulo. Data will be obtained from the electronic medical record system from 2011 to 2019.