Synthesis, characterization and biological assays of novel chelates of oligoelements from hydrolysed proteins of bovine milk serum

• Grant number: 09/16925-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2010
• End date: February 28, 2011
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Principal Investigator: Regina Celia Galvao Frem
• Grantee: Vitória Gomes Nogueira de Oliveira
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

This work deals with the synthesis and characterization of novel Mn, Fe, Co, Cu and Zn chelates containing hydrolyzed proteins of bovine milk serum. The idea consists in to prepare and use metallic chelates containing natural ligands as alimentary supplementation in ovines. Recent studies have demonstrated a considerable increase of the oligoelement bioavailability when administrated in the chelating fashion, in comparison with inorganic salts commonly used as mineral sources. Besides that the milk serum, a proteic sub product from lacticínio industry, has been inadvertently discarded in rivers carrying out serious ambient risks. This project will have the collaboration of Prof. Dr. Rubens Monti (Laboratório de Enzimologia, Faculdade de Ciências Farmacêuticas, UNESP-Araraquara) and Prof. Dr. Otávio Campos Neto (Faculdade de Medicina Veterinária e Zootecnia, UNESP-Botucatu).