Development of a spectrophotometric method for quantitative determination of metformin

• Grant number: 07/04024-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2007
• End date: November 30, 2008
• Field of knowledge: Health Sciences - Pharmacy - Medicines Analysis and Control
• Principal Investigator: Marta Maria Duarte Carvalho Vila
• Grantee: Karin dos Santos Proença
• Host Institution: Centro de Ciências Biológicas e Saúde. Universidade de Sorocaba (UNISO). Sorocaba , SP, Brazil

Abstract

The aim of this work is the development of a quantitative spectrophotometric method for the determination of metformin. The method will be based on the reaction between metformin and copper ions in basic medium to give a colored complex. Determined the best conditions for the development of the reaction the method will be validated. (AU)