Effect of colagen cross-linkers in the adhesive interfaces: evaluation of mechanical nanoproperties

• Grant number: 08/03213-7
• Support Opportunities: Scholarships abroad - New Frontiers
• Start date: May 01, 2008
• End date: December 31, 2008
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Paulo Henrique dos Santos
• Grantee: Paulo Henrique dos Santos
• Host Investigator: Ana Karina Barbieri Bedran Russo
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil
• Institution abroad: University of Illinois at Chicago (UIC), United States

Abstract

The aim of this study is to evaluate the effect of cross-linkers (glutaraldehyde and proanthocyanidin) in the values of nanohardness and elastic modulus in different sites of hybrid layer after the application of adhesive system to dentin. Eighteen human molars will be used in this study. The oclusal surface will be planned until exposure of dentin. The teeth will be divided in three experimental groups (n=6) according to the cross-linkers used: group 1 (without cross-linker and Single Bond adhesive system), group 2 (glutaraldehyde and Single Bond) and group 3 (proanthocyanidin and Single Bond). On the prepared surface, the resin-based composite Z250 will be applied. After 24 hours, the specimens of each experimental group will be sliced and imbibed in acrylic resin. The values of nanohardness and elastic modulus will be evaluated in the Custom Triboindenter in the following regions: dentin (under the hybrid layer), hybrid layer, top of adhesive layer and resin-based composite area. The specimens will be stored in Hanks solution or collagenase during 3 and 6 months and the values of nanohardness and elastic modulus will be calculated. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DOS SANTOS, P. H.; KAROL, S.; BEDRAN-RUSSO, A. K. B.. Nanomechanical properties of biochemically modified dentin bonded interfaces. Journal of Oral Rehabilitation, v. 38, n. 7, p. 541-546, JUL 2011. (08/03213-7)

DOS SANTOS, PAULO HENRIQUE; KAROL, SACHIN; PEDRAN-RUSSO, ANA KARINA. Long-term nano-mechanical properties of biomodified dentin-resin interface components. JOURNAL OF BIOMECHANICS, v. 44, n. 9, p. 1691-1694, JUN 3 2011. (08/03213-7)

PAVAN, SABRINA; DOS SANTOS, PAULO H.; BERGER, SANDRINE; BEDRAN-RUSSO, ANA KARINA B.. THE EFFECT OF DENTIN PRETREATMENT ON THE MICROTENSILE BOND STRENGTH OF SELF-ADHESIVE RESIN CEMENTS. JOURNAL OF PROSTHETIC DENTISTRY, v. 104, n. 4, p. 258-264, OCT 2010. (08/03213-7)