City: São Paulo
See other companies with research projects supported by PIPE ProgramMicroorganisms are important sources of molecules, many of which have already been described with application in the pharmaceutical field. The fungus Exserohilum rostratum isolated from an endemic plant of the Caatinga produces the secondary metabolite annularin I. This secondary metabolite in vitro studies promoted the proliferation of endothelial cells and human fibroblasts and showed a…
Secondary metabolites produced by microorganisms are known due to their several biotechnological applications, and are also good lead compounds suitable for further modification during drug development. Annularins is a class of molecules commonly found in fungi, and annularin I have moderate antimicrobial action in pathogens commonly present in infections. In previous in vitro studies on …
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