Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Janaina Natalia de Souza da Cruz in research grants and scholarships supported by FAPESP.
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Streptococcus mutans, the primary etiologic agent of dental caries, colonizes the oral cavity almost exclusively as biofilms on the tooth surface. The pathogenic potential of S. mutans is attributed to its excellent mechanisms of biofilm formation, rapid production of large amounts of lactic acid and high tolerance to acidic pH. The presence of sucrose favors the mechanisms of colonizatio…
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