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Universidade de Santo Amaro (UNISA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Luiz Henrique da Silva Nali in research grants and scholarships supported by FAPESP.
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Human Endogenous Retroviruses (HERVs) are fossil retroviruses that infected germ cells of our ancestors millions of years ago. As with other retroviruses, the genome integration stage is characteristic of the viral replicative cycle. This resulted in integration into these germ cells and was a fundamental step in the endogenization process of the virus in the genome of our ancestors and i…
Respiratory viruses represent a significant portion of respiratory infections, especially during childhood, where many of these infections can culminate in hospitalizations. Today, in Brazil, respiratory infections are the 5th leading cause of death. In addition, many respiratory viruses, which can result in more severe infections, are not prevented by vaccines. Also, it is important to m…
Human endogenous retroviruses (HERVs), which represent approximately 8% of the human genome, result from the integration of viral elements into the germline of our ancestors. Their structure is similar to that of classical retroviruses, containing core genes (gag, pol/pro and env) and long terminal repeats (LTRs). Although frequently associated with autoimmune diseases, HERVs also exert p…
Introduction: HERVs are present in 8% of the human genome, being remnants of past viral infections that generated integrations into the human genome throughout the evolution of the Mendelian form. Although many HERVs are considered inactive and nonfunctional, they are not expressed. Recent studies have revealed that some of the HERVs, mainly HERV-K and HERV-W, have their expression direct…
Schizophrenia is defined as a mental disorder with unknown biological etiology, with biopsychosocial aggravations, which affects people all over the world, with symptoms of psychosis throughout life, in general, patients are diagnosed around the second decade of life. Studies point to high rates of inflammatory response during the development of the clinical picture of schizophrenia, thus…
Endogenous Retroviruses (ERVs) are ancestral viruses that have infected virtually all vertebrates, including humans. In the course of human evolution, Human Endogenous Retroviruses (HERVs) have undergone several mutational events and many have been silenced. Despite these events, HERVs have several important roles in human physiology. Among them is a regulation in the expression of genes …
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 5 / 4 | Completed scholarships in Brazil |
| 9 / 8 | All research grants and scholarships |
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