CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Undergraduation in Biological Sciences from the University Center Barao de Maua (2003), Master Degree of Molecular and Cell Biology at the University of São Paulo (2006) and PhD in PhD in Molecular and Cell Biology at the University of São Paulo, whose research was performed in the all at the National Institutes of Health, USA (2010). He is currently developing a research project at the Laboratory of Intracellular Protein Traffic in the Medical School of Ribeirao Preto, University of São Paulo. Has experience in the areas of Molecular and Cell Biology, Biochemistry, Immunology and Histology. (Source: Lattes Curriculum)
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The HIV-1 (human immunodeficiency virus type 1), targets CD4+ T lymphocytes and this leads to a severe reduction in the number of T cells CD4+, resulting in the collapse of the immune system and progression of acquired immunodeficiency syndrome (AIDS). The successful replication of HIV-1 depends on its accessory proteins; among them is Nef. The product of the nef gene represents the main …
Infection of human immunodeficiency virus, HIV-1, results in impaired function of the immune system that leads to clinical manifestations of AIDS. The genome of HIV-1 encodes nine proteins, among them is the accessory protein Nef. Although Nef lacks enzymatic activity, it has the capacity to change signaling pathways and to interfere with intracellular protein trafficking machinery, there…
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