CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Senior Analyst and Lecturer at the Instituto Israelita de Ensino e Pesquisa Albert Einstein. Holds a Ph.D. in Medicine from the Federal University of São Paulo (UNIFESP - EPM), where she conducted research on the Renin-Angiotensin-Aldosterone System, focusing on Angiotensin-Converting Enzyme, site-directed mutations, and recombinant protein production. Research includes studying the interactions of Angiotensin-Converting Enzyme (ACE) with inhibitors and substrates. Sandwich Ph.D. at Texas AM University in 2014.Master's degree in Biotechnology at the Nuclear and Energy Research Institute (IPEN/CNEN/USP) in 2009, with an emphasis on Molecular Biology and human protein production. Graduation in Biological Sciences from the São Paulo State University Júlio de Mesquita Filho (UNESP) in 2005. (Source: Lattes Curriculum)
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Hypertension is a worldwide health problem that is emerging in the population as a major public health challenges and considered a major risk factor for cardiovascular and renal disease. Several studies have focused on the renin-angiotensin system, which is described as an endocrine system, where renin, an aspartyl endopeptidase, cleaves angiotensinogen in the Leu10-Val11 bond and release…
Several cellular mechanisms participate in the development of diabetes-induced cardiac dysfunction. A role of the tissue renin-angiotensin system (RAS) in diabetic cardiomyopathy has been demonstrated by clinical and experimental studies. Diabetes is also a disease of chronic inflammation; the latter having deleterious effects on the cardiovascular function. The nuclear factor kB (NF-kB) …
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