Abstract
Thyroid hormones play a central role in Central Nervous System (CNS) development, besides being essential for some of the most important physiologic parameters. Deiodination involves the conversion of T4 into T3, a process catalyzed by D1, D2 and D3 enzymes, which can promote the activation or inactivation of the thyroid hormones in response to the specific needs of the tissues. D3 is res…