Abstract
The loss of dopaminergic neurons in Parkinson's disease (PD) is accompanied by neuroinflammation, which is mediated by glial cells, mainly microglia. However, the cause of origin and development of neuroinflammation was not elucidated and probably it is perpetuating and amplifying the progression of this disease. The dopamine precursor, L-DOPA, is the most efficient treatment for PD motor…