Abstract
The aim of this project is to improve the understanding of the neurodegenerative process of Parkinson´s disease (PD). The major neuropathological alteration of PD is a progressive degeneration of dopaminergic neurons of the substantia nigra pars compacta, with cytoplasmatic inclusions enriched with alpha-synuclein and ubiquitin proteins, also known as Lewy´s bodies. Postmortem studies in …