Larissa Menezes dos Reis

• Abstract

  Macrophages are heterogeneous and plastic populations of immune system cells that respond to environmental stimuli by modifying their functions within a wide spectrum of phenotypes, whereas M1 (inflammatory) and M2 (anti-inflammatory/repair) are the extreme subtypes of macrophages. A characteristic related to macrophages polarization is their metabolic adaptation, M1 type presents increas…

  Modulation of mitochondrial dynamics as an approach for macrophage repolarization in cancer treatment, BP.PD

• Abstract

  The triple-negative breast cancer disease is characterized by the absence of progesterone and estrogen hormone receptors and HER2 membrane receptor, therefore is unresponsive to conventional treatments of disease. Among others, changes in the cellular metabolism are the molecular basis for the emergence and progression of the triple-negative phenotype, indicating that these alterations ca…

  Study of alternative anaplerotic sources of the TCA as new targets against triple-negative breast cancer, BP.DD

• Abstract

  The Triple-negative breast cancer is characterized by the absence of progesterone and estrogen hormone receptors and HER2 membrane receptor, therefore, is unresponsive to conventional treatment of disease. Among others, changes in the cellular metabolism are the molecular basis for the emergence and progression of triple-negative, indicating that it can provide good therapeutic targets. I…

  Search for alternative anaplerotic sources of the TCA as new targets against triple-negative breast cancer, BP.MS

(Only some records are available in English at this moment)