CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Colômbia
graduate at Microbiología Industrial from Pontificia Universidad Javeriana (2007). Has experience in Parasitology, acting on the following subjects: región intergénica, biología molecular y bioquimica de t. cruzi, trypanosoma rangeli and histona h2a. (Source: Lattes Curriculum)
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This proposal aims to elucidate the mechanism(s) involved in the trypanocidal effect exhibited by the tetraethylthiuram disulfide drug, - commercially known as Disulfiram ® (herein named as DSF), on the parasite causing of Chagas's disease, the Trypanosoma cruzi. The DSF is susceptible to metabolic breakdown, and therefore their metabolic derivatives will be also analysed; so it will be n…
Both, information obtained by our lab on the role P5CDH in Trypanosoma cruzi metabolism and biology, and available information in the literature support the role of this enzyme in several physiological processes in the African trypanosome (T. brucei) and its intermediate host Glossina morsitans (tsetse fly). This proposal intends to assess the phenotype of conditioned mutant null cells fo…
| 2 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 2 | All Scholarships |
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