Abstract
This project aims to develop and characterize a strategy for prophylactic vaccination against dengue virus serotype 2 (DENV2), based on NS3 protein helicase domain (NS3H) combined with three adjuvants and injected subcutaneously in mice. To do this, will be cloned and expressed the genes encoding NS3H and a non-toxic heat-labile toxin (LTG33D) from enterotoxigenic E. coli (ETEC) in recomb…