Abstract
RET gene is an oncogene located on chromossome 10q11.2 that encodes a tyrosine kinase transmembrane receptor associated to cell growth, migration, and differentiation signaling pathways. Mutations that activates RET in germinative cell lines are associated to the inherited dominant autosomal syndrome called Multiple Endocrine Neoplasia type 2 that presents Medullary Thyroid Carcinoma (MTC…